Endocrine Abstracts

Impaired insulin action is a characteristic feature of type 2 diabetes and skeletal muscle is the principal tissue for peripheral glucose disposal. Aims: To determine if after prolonged culture human muscle cells from characterised type 2 diabetes patients have defects of insulin action compared to controls. Design: After attaining local Ethical Committee approval six compliant type 2 diabetic patients with severe clinical insulin resistance, on greater than 100 units of insul...

Impaired insulin action is a characteristic feature of type 2 diabetes and skeletal muscle is the principal tissue for peripheral glucose disposal. Aims: To determine if after prolonged culture human muscle cells from characterised type 2 diabetes patients have defects of insulin action compared to controls. Design: After attaining local Ethical Committee approval six compliant type 2 diabetic patients with severe clinical insulin resistance, on greater than 100 units of insul...